Step 1: Install Required Packages
First we need to install required packages for Skype
# yum install fontconfig freetype glib2 libXScrnSaver libXi libXrandr libXrender libXv qt qt-x11 zlib qtwebkit  alsa-lib  libSM libstdc++ pulseaudio-libs 
Step 2: Download and Extract Skype Source
Download latest Skype source code using following command and extract it in /usr/src/ directory.
# cd /usr/src
# wget http://www.skype.com/go/getskype-linux-dynamic
# tar xjf skype-4.2.0.11.tar.bz2
# mv skype-4.2.0.11 skype 
Step 3: Create Skype Launch Script
We need to create scrip to launch skype using command line. Create a new file /usr/bin/skype and add following content.
# vim /usr/bin/skype
#!/bin/sh
export SKYPE_HOME="/usr/src/skype"
$SKYPE_HOME/skype --resources=$SKYPE_HOME $*
Make this script executable using chmod command.
# chmod 755 /usr/bin/skype
Step 4: Setup Required files
We need to create symbolic links of required files in system folder
# ln -s /usr/src/skype/icons/SkypeBlue_48x48.png /usr/share/icons/skype.png
# ln -s /usr/src/skype/icons/SkypeBlue_48x48.png /usr/share/pixmaps/skype.png
# ln -s /usr/src/skype/skype.desktop /usr/share/applications/skype.desktop
Also copy following directories content to system directories.
# cp /usr/src/skype/sounds/* /usr/share/sounds/
# cp /usr/src/skype/lang/* /usr/share/lang/
Step 5: Launch Skype using Command line
Use skype comamnd to launch Skype from command line and accept terms and conditions for first time. After accepting terms you will get Skype login screen